Drug related morbidity and mortality updating the cost of illness
Conclusion: The present study identified high-risk drugs for TRPs, which can be used as identification of targeting approach TRPs.
Such an approach would improve care provided to patients and can inform health care policies.
Method Setting The present study was carried out in eleven outpatient departments including respiratory, endocrine, and cardiovascular in five hospitals in the northern, central, and southern areas of Jordan.
These hospitals represent major hospitals in distinctive areas of Jordan and include King Abdullah University Hospital (KAUH), a teaching hospital affiliated with the Jordan University of Science and Technology in Irbid; Jordan University Hospital, a teaching hospital affiliated with the University of Jordan in Amman; Al-Basheer Hospital, a public hospital in Amman; Princess Basma Hospital, a public hospital in Irbid; and Al-Karak Hospital, a public hospital in Al-Karak.
Thus, there is a need for a large, multicenter study to identify medications that are mostly associated with TRPs in such health care settings.
Such an approach will be useful for pharmacists in supporting patient medication use by addressing TRPs, as opposed to medications that would be associated with serious consequences in the case of error.
The high impact associated with TRP issues can provide a strong case for pharmacist service to address such important problems, particularly serious, clinically significant TRPs.
Additionally, the traditional high-alert drug approach was limited to drugs that have a low safety margin in which errors associated with the use are devastating.Setting: Outpatient departments of five public and teaching hospitals in Jordan.Method: TRPs and drugs most commonly implicated with TRPs were assessed for patients recruited from outpatient clinics in five major hospitals in Jordan using a standardized and validated pharmaceutical care manual.Cardiovascular medications were the most common drugs implicated with multiple subtypes of TRPs – most commonly, allergic reaction or undesirable effect (88.5%), drug product not available (87.3%), safety interaction issues (81.8%), a need for additional or more frequent monitoring (78.0%), and more effective drugs available (77.2%).Hypertension, diabetes mellitus, and dyslipidemia were the most common diseases associated with different subtypes of TRPs.